Synonyms :

EDF, BCDFII, TRF

Description :

IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Recombinant rat IL-5 is a 26.0 kDa disulfide-linked homodimeric protein containing two 113 amino acid chains.

Catalog #:

400-05

Source :

E.coli

Purity :

Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin Level :

Endotoxin level is less than 0.1 ng per μg (1EU/μg).

Biological Activity :

The ED ₅₀ was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is < 0.5 ng/ml, corresponding to a specific activity of > 2 x 10⁶units/mg.

AA Sequence :

MEIPMSTVVK ETLIQLSTHR ALLTSNETMR LPVPTHKNHQ LCIGEIFQGL DILKNQTVRG GTVEILFQNL SLIKKYIDGQ KEKCGEERRK TRHFLDYLQE FLGVMSTEWA MEV

PubMed Link :

IL-5+AND+rat

Country of Origin :

USA

Special Sizes: 
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Usage: 
For Research Use Only. Not for use in diagnostic or therapeutic procedures.